Hydrolyzed Sodium Hyaluronate with 3000 Da molecular weight is becoming increasingly popular among cosmetic formulators and personal care manufacturers thanks to its unique balance of skin penetration and surface hydration. However, incorrect usage or misunderstandings of its properties may lead to formulation instability or reduced efficacy.
In this article, we will provide a comprehensive application guide, highlight key usage tips, and address frequently encountered issues during product development.
This mid-low molecular weight form of HA is ideal for:
Deep yet gentle hydration
Enhancing skin elasticity
Strengthening the skin barrier
Supporting active ingredient delivery
Creating lightweight, non-greasy formulations
Its versatile solubility and compatibility make it suitable for creams, serums, masks, emulsions, and sprays.
To ensure the best performance in your formulations, follow these best practices:
| Parameter | Recommended Range |
|---|---|
| Usage level | 0.1% – 1.0% |
| Solvent | Deionized or purified water |
| Hydration temperature | Room temp (20–25°C) or slightly warm (≤40°C) |
| pH range | 4.0 – 7.0 (ideal for most skin care) |
| Inclusion point | Post-emulsification or cool-down phase |
Issue: Powder forms clumps when added too quickly into water.
Solution: Add slowly while stirring continuously or use a vortex mixer. Pre-wet with a small amount of glycerin can also improve dispersion.
Issue: Overuse of HA leads to tackiness.
Solution: Stay within recommended dosage. Combine with lightweight emollients or silicone alternatives to balance texture.
Issue: HA degrades in overly acidic or alkaline environments.
Solution: Adjust formulation pH to remain between 4.5–6.5. Avoid strong acids or bases post-addition.
Issue: HA interacts poorly with high concentrations of cationic surfactants or alcohol.
Solution: Conduct compatibility tests with your preservative system and avoid excessive ethanol content.
Issue: Degradation occurs if HA is added during emulsification at >70°C.
Solution: Always add during the cool-down phase (<40°C) to preserve molecular integrity.
Hydrating facial serums
Barrier-repair creams
After-sun recovery gels
Anti-aging masks and sleeping packs
Sensitive skin formulas and baby care products
It’s a favorite for formulators who want the benefits of both surface-level and intra-epidermal hydration without risking irritation.
✅ Combine with ceramides, niacinamide, or peptides for boosted skin benefits.
✅ Store powder in a cool, dry place. Avoid humidity exposure.
✅ Conduct stability tests on finished products to ensure no breakdown over time.
At Runxin Biotech, we offer high-purity, cosmetic-grade hydrolyzed sodium hyaluronate with full documentation, flexible MOQ, and custom molecular options.
Need a formulation consultation or sample?
Contact us now – our R&D team is ready to assist.