Introduction
With 28 years of specialized manufacturing expertise, Runxin introduces Acetylated Sodium Hyaluronate—a revolutionary raw material powder engineered for dual-phase skin permeation. This comprehensive guide addresses common formulation challenges while providing scientifically-backed solutions for optimal product performance in advanced skincare applications.
Technical Advantages of Acetylated Sodium Hyaluronate
Enhanced lipophilic properties for improved skin barrier penetration
Dual-phase compatibility in both water-based and oil-based formulations
Superior stability against enzymatic degradation
Optimal for advanced skincare, serums, and targeted treatment products
Expert Application Guidelines
Challenge: Achieving uniform dispersion in both aqueous and oil phases
Solution:
Pre-disperse in ethanol or glycerin before incorporation
Utilize high-shear mixing at 35-45°C for optimal hydration
Implement phase-by-phase addition protocols
Challenge: Maintaining acetyl group integrity during processing
Solution:
Control processing temperature below 50°C
Maintain pH between 5.5-6.5 for group stability
Incorporate protective antioxidant systems
Challenge: Balancing penetration enhancement with product safety
Solution:
Optimize concentration between 0.2%-1.0%
Combine with penetration-enhancing carriers
Conduct skin compatibility testing
Challenge: Managing texture in final formulations
Solution:
Blend with sensory modifiers for improved spreadability
Adjust viscosity with complementary thickeners
Optimize with lightweight emollients
Recommended Applications
Advanced Serums: Targeted skin barrier penetration systems
Dual-Phase Formulations: Water-in-oil and oil-in-water emulsions
Professional Treatments: Clinical-grade skincare solutions
Innovative Delivery Systems: Enhanced penetration products
Runxin Quality Assurance
28 Years Manufacturing Excellence: Consistent quality and reliability
Advanced Acetylation Technology: Precise molecular modification
Rigorous Quality Control: Comprehensive analytical testing
Global Compliance: Meets international regulatory standards
5 Google-Optimized Q&A About Acetylated Sodium Hyaluronate
Q1: What is acetylated sodium hyaluronate and how does it differ from regular HA?
A: Acetylated sodium hyaluronate is a modified form where acetyl groups are added to the HA molecule, enhancing its lipophilic properties and skin penetration ability while maintaining excellent hydration capacity.
Q2: Can acetylated sodium hyaluronate be used in oil-based formulations?
A: Yes, its modified structure provides better compatibility with oil phases compared to regular HA, making it suitable for dual-phase and emulsion formulations.
Q3: What concentration range is effective for acetylated sodium hyaluronate?
A: Typically 0.2%-1.0%, depending on the desired penetration enhancement and formulation type. Start with lower concentrations for initial testing.
Q4: How does acetylation affect the stability of hyaluronic acid?
A: Acetylation improves stability against hyaluronidase degradation and enhances compatibility with a wider range of formulation ingredients.
Q5: Is special processing required when using acetylated sodium hyaluronate powder?
A: We recommend pre-dispersion in suitable solvents and temperature-controlled hydration below 50°C to preserve the acetyl groups' functionality.
Conclusion
Runxin's Acetylated Sodium Hyaluronate represents a significant advancement in hyaluronic acid technology, offering formulators unprecedented opportunities in skincare innovation. Our 28 years of manufacturing expertise ensures consistent quality and performance excellence.
Contact Runxin today for technical documentation, samples, and expert formulation support.
