The "L-" prefix on sodium hyaluronate is a brand marketing term, not a distinct chemical entity. The correct INCI name is Sodium Hyaluronate (CAS 9067-32-7). The sodium salt is preferred over the free acid for its higher solubility and near-neutral pH. Performance depends on molecular weight distribution, not naming. Multi-weight formulations (high, medium, and low MW fractions) are standard, as each range affects different skin layers. Sourcing requires verifying CoA parameters: MW, glucuronic acid content, protein residue, endotoxin, heavy metals, microbial limits, and loss on drying. Grade alignment and certifications are essential.

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