RUNXIN Acetylated Sodium Hyaluronate is an innovative hyaluronic acid derivative obtained through directional acetyl group modification technology, with a precisely controlled molecular weight of 20,000–50,000 Da. This advanced ingredient features both lipophilic and hydrophilic properties, overcoming the limitation of traditional hyaluronic acid being only water-soluble.
With significantly increased lipid and oil affinity, it delivers dual moisturizing effects, strengthens the stratum corneum barrier, improves skin elasticity, and relieves dryness and roughness. This makes it ideal for high-end cosmetics, skincare, and medical oil-based dressings.
Acetylated Sodium Hyaluronate
Runxin Biotech
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Acetylated Sodium Hyaluronate is an innovative hyaluronic acid derivative obtained through directional acetyl group modification technology, with a precisely controlled molecular weight of 20,000–50,000 Da. This advanced ingredient features both lipophilic and hydrophilic properties, overcoming the limitation of traditional hyaluronic acid being only water-soluble.
With significantly increased lipid and oil affinity, it delivers dual moisturizing effects, strengthens the stratum corneum barrier, improves skin elasticity, and relieves dryness and roughness. This makes it ideal for high-end cosmetics, skincare, and medical oil-based dressings.
Dual Affinity – Combines lipophilic and hydrophilic properties for broader formulation possibilities.
Deep Penetration – Reaches skin depth up to 100 μm, double that of standard hyaluronic acid.
Enhanced Stability – Strong resistance to hyaluronidase (13× higher than standard HA) for long-lasting hydration.
Oil Phase Compatible – Stable in oil-based formulations without precipitation.
Versatile Applications – Suitable for facial creams, sunscreens, oil-based serums, and medical dressings.
INCI Name: Sodium Acetylated Hyaluronate
Molecular Formula: (C14+2XH20+2XNO11+XNa)ₙ (x represents degree of acetylation)
Average Molecular Weight: 20,000–50,000 Da
Degree of Acetylation: 20–30%
Appearance: White or light yellow powder, odorless
Active Content: ≥95%
Packaging: 1 kg/aluminum foil bag, 25 kg/drum
Cosmetics: Premium moisturizers, anti-aging creams, sunscreens
Skincare: Oil-based serums, night creams, nourishing masks
Medical: Oil-based wound dressings, dermatological ointments
1. What makes Acetylated Sodium Hyaluronate different from regular Hyaluronic Acid?
It has both oil and water solubility, deeper skin penetration, and stronger enzyme resistance, making it more versatile in formulations.
2. Can it be used in oil-based formulations without precipitation?
Yes. Its lipophilic property ensures excellent stability in oil phases.
3. What molecular weight is best for my formulation?
This product has a controlled molecular weight of 20,000–50,000 Da, ideal for deep hydration and barrier reinforcement.
4. Is it safe and certified for cosmetic use?
Yes. It complies with FDA, ISO, cGMP, Halal, REACH, COSMOS standards.
5. How should it be stored?
Store in a cool, dry place away from light and moisture. Keep packaging tightly sealed after opening.
With over 28 years of experience, RUNXIN Biotechnology has perfected the production of sodium hyaluronate, ensuring high-quality, safe, and effective products for the cosmetic industry. Our cosmetic-grade sodium hyaluronate is manufactured with the highest industry standards, including NSF, ISO, GMP, and HACCP certifications. We focus on providing customizable solutions that meet the specific needs of your skincare formulations.
Acetylated Sodium Hyaluronate is an innovative hyaluronic acid derivative obtained through directional acetyl group modification technology, with a precisely controlled molecular weight of 20,000–50,000 Da. This advanced ingredient features both lipophilic and hydrophilic properties, overcoming the limitation of traditional hyaluronic acid being only water-soluble.
With significantly increased lipid and oil affinity, it delivers dual moisturizing effects, strengthens the stratum corneum barrier, improves skin elasticity, and relieves dryness and roughness. This makes it ideal for high-end cosmetics, skincare, and medical oil-based dressings.
Dual Affinity – Combines lipophilic and hydrophilic properties for broader formulation possibilities.
Deep Penetration – Reaches skin depth up to 100 μm, double that of standard hyaluronic acid.
Enhanced Stability – Strong resistance to hyaluronidase (13× higher than standard HA) for long-lasting hydration.
Oil Phase Compatible – Stable in oil-based formulations without precipitation.
Versatile Applications – Suitable for facial creams, sunscreens, oil-based serums, and medical dressings.
INCI Name: Sodium Acetylated Hyaluronate
Molecular Formula: (C14+2XH20+2XNO11+XNa)ₙ (x represents degree of acetylation)
Average Molecular Weight: 20,000–50,000 Da
Degree of Acetylation: 20–30%
Appearance: White or light yellow powder, odorless
Active Content: ≥95%
Packaging: 1 kg/aluminum foil bag, 25 kg/drum
Cosmetics: Premium moisturizers, anti-aging creams, sunscreens
Skincare: Oil-based serums, night creams, nourishing masks
Medical: Oil-based wound dressings, dermatological ointments
1. What makes Acetylated Sodium Hyaluronate different from regular Hyaluronic Acid?
It has both oil and water solubility, deeper skin penetration, and stronger enzyme resistance, making it more versatile in formulations.
2. Can it be used in oil-based formulations without precipitation?
Yes. Its lipophilic property ensures excellent stability in oil phases.
3. What molecular weight is best for my formulation?
This product has a controlled molecular weight of 20,000–50,000 Da, ideal for deep hydration and barrier reinforcement.
4. Is it safe and certified for cosmetic use?
Yes. It complies with FDA, ISO, cGMP, Halal, REACH, COSMOS standards.
5. How should it be stored?
Store in a cool, dry place away from light and moisture. Keep packaging tightly sealed after opening.
With over 28 years of experience, RUNXIN Biotechnology has perfected the production of sodium hyaluronate, ensuring high-quality, safe, and effective products for the cosmetic industry. Our cosmetic-grade sodium hyaluronate is manufactured with the highest industry standards, including NSF, ISO, GMP, and HACCP certifications. We focus on providing customizable solutions that meet the specific needs of your skincare formulations.
