5000 Da Sodium Hyaluronate | Runxin cGMP Certified Production

Manufacturer Profile: Runxin – Pioneering Low Molecular Weight HA Since 1998
Runxin represents 28 years of manufacturing excellence in specialized sodium hyaluronate production, with particular expertise in low molecular weight fractions. Our advanced production facilities maintain comprehensive international certifications including cGMP, ISO9001, ISO22000, ISO13485, HACCP, HALAL, and FSSC22000, ensuring pharmaceutical-grade quality across all operations. Serving innovative skincare and nutraceutical companies across 70+ countries, we combine proprietary enzymatic cleavage technology with precision purification methods to deliver accurately calibrated low molecular weight sodium hyaluronate with verified biological activity.

Product Overview: 5000 Da Sodium Hyaluronate
Runxin's 5000 Da Sodium Hyaluronate is engineered through controlled enzymatic processing to achieve precise molecular weight targeting ideal for enhanced bioavailability applications. This specialized material undergoes rigorous quality verification to ensure consistent 5000 Da (±400 Da) molecular weight distribution, making it particularly effective for formulations requiring efficient cellular uptake and deep tissue penetration. The optimized molecular size enables superior functionality in advanced dermal delivery systems while maintaining the natural water-binding characteristics of hyaluronic acid.

Key Advantages

• Precision Calibration: Consistent 5000 Da molecular weight through controlled enzymatic processing

• Enhanced Cellular Absorption: Optimal molecular size for efficient transmembrane transport

• Deep Tissue Penetration: Facilitates delivery to epidermal and dermal layers

• Preserved Bioactivity: Maintains natural receptor recognition and binding capabilities

• Multi-Application Compatibility: Suitable for cosmetic, pharmaceutical, and nutraceutical formulations

Technical Specifications

• Appearance: White to off-white free-flowing powder

• Molecular Weight: 5000 Da (±400 Da)

• Purity: ≥97% (HPLC)

• Loss on Drying: ≤7%

• pH (1% solution): 6.0-7.0

• Viscosity (1% solution): 50-150 mPa·s

• Protein Content: ≤0.03%

• Heavy Metals: ≤4 ppm

• Microbiological Profile:

• Total Plate Count: <80 CFU/g

• Yeast & Mold: <15 CFU/g

• E. coli: Absent in 10g

• Salmonella: Absent in 25g

• Solubility: ≥99% in water

• Particle Size: 120-250 mesh

• Certifications: cGMP, ISO9001, ISO22000, ISO13485, HACCP, HALAL, FSSC22000

Applications

• Advanced transdermal delivery systems

• Cellular-level hydrating serums

• Professional aesthetic formulations

• Nutraceutical absorption enhancement

• Regenerative skincare products

• Pharmaceutical precursor applications

FAQs About 5000 Da Sodium Hyaluronate

1. What makes 5000 Da molecular weight particularly effective for skincare absorption?
   The 5000 Da molecular weight represents the optimal threshold for efficient skin penetration while maintaining significant water-binding capacity. This size allows effective transit through skin barriers to reach living epidermal cells where it can directly influence cellular hydration and signaling processes.

2. How does enzymatic processing ensure consistent 5000 Da molecular weight?
   Our proprietary enzymatic methodology uses specific hyaluronidases that cleave HA chains at predetermined sites, enabling precise control over molecular weight reduction. This approach preserves bioactive sequences while achieving the target 5000 Da size with minimal batch-to-batch variation.

3. What formulation benefits does 5000 Da HA offer compared to other molecular weights?
   This specific molecular weight demonstrates exceptional stability in complex formulations, shows reduced viscosity for easier processing, and maintains enhanced penetration capabilities without compromising moisturizing performance. It's particularly valuable in systems requiring both deep delivery and surface hydration.

4. Can 5000 Da sodium hyaluronate be used in oral supplement formulations?
   Yes, its lower molecular weight enhances intestinal absorption and systemic bioavailability. Research indicates that 5000 Da HA shows improved transport across intestinal epithelium, making it highly suitable for nutraceutical applications targeting joint and skin health from within.

5. What analytical verification do you provide for molecular weight accuracy?
   We employ advanced GPC-MALS (Gel Permeation Chromatography with Multi-Angle Light Scattering) analysis to verify molecular weight distribution, ensuring each batch maintains the specified 5000 Da target. Complete analytical certificates accompany every shipment, providing transparent quality verification.

Why Choose Runxin for Precision Molecular Weight HA

• 28 Years of Specialized Manufacturing: Expertise in controlled molecular weight HA production since 1998

• Proprietary Enzymatic Technology: Precision cleavage for accurate molecular weight control

• Comprehensive Quality Systems: Full certification under cGMP, ISO9001, ISO22000, ISO13485, HACCP, HALAL, and FSSC22000

• Advanced Analytical Capabilities: Sophisticated molecular characterization methods

• Global Technical Support: Formulation guidance and application development assistance

Partner with Low Molecular Weight HA Specialists
Select Runxin for your 5000 Da sodium hyaluronate requirements and benefit from our 28 years of specialized manufacturing expertise. Contact us today to request samples, analytical documentation, or discuss your specific application needs. Experience the advantages of precisely engineered molecular weight hyaluronic acid from an industry leader with nearly three decades of technological innovation and quality commitment.

today for technical support, pricing, and tailored ingredient solutions!