Hydrolyzed Sodium Hyaluronate 3000 Da
Runxin Biotech
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Manufacturer Profile: Runxin – Precision Hydrolysis Specialists Since 1998
Runxin brings 28 years of focused expertise in advanced hyaluronic acid technologies, specializing in controlled molecular weight sodium hyaluronate production. Our sophisticated manufacturing facilities maintain comprehensive international certifications including cGMP, ISO9001, ISO22000, ISO13485, HACCP, HALAL, and FSSC22000, with specialized capabilities in enzymatic hydrolysis processes. Serving advanced skincare and pharmaceutical developers across 70+ countries, we combine proprietary hydrolysis technology with precision purification methods to deliver low molecular weight sodium hyaluronate with verified molecular characteristics and exceptional bioavailability.
Product Overview: 3000 Da Hydrolyzed Sodium Hyaluronate
Runxin's 3000 Da Hydrolyzed Sodium Hyaluronate represents a breakthrough in low molecular weight HA technology through controlled enzymatic hydrolysis. This precisely engineered material undergoes specialized processing to achieve a consistent molecular weight of 3000 Da (±500 Da), enabling superior skin penetration and cellular-level hydration. The proprietary hydrolysis process preserves the biological activity while significantly reducing molecular size, making it particularly effective for advanced skincare formulations targeting deep epidermal delivery and enhanced bioavailability.


Key Advantages
Precise Molecular Control: Consistent 3000 Da molecular weight through proprietary hydrolysis
Enhanced Skin Penetration: Optimal size for efficient transdermal delivery
Cellular-Level Hydration: Reaches deeper skin layers for fundamental moisturization
Preserved Bioactivity: Maintains HA's natural water-binding capacity
Formulation Versatility: Excellent compatibility with various delivery systems
Technical Specifications
Appearance: White to off-white fine powder
Molecular Weight: 3000 Da (±500 Da)
Purity: ≥98% (HPLC)
Loss on Drying: ≤6%
pH (1% solution): 5.8-6.8
Viscosity (1% solution): 20-80 mPa·s
Protein Content: ≤0.02%
Heavy Metals: ≤3 ppm
Microbiological Profile:
Total Plate Count: <50 CFU/g
Yeast & Mold: <10 CFU/g
E. coli: Absent in 10g
Salmonella: Absent in 25g
Solubility: ≥99.5% in water
Particle Size: 150-300 mesh
Certifications: cGMP, ISO9001, ISO22000, ISO13485, HACCP, HALAL, FSSC22000
Applications
Advanced anti-aging serums with deep penetration
Targeted dermal delivery systems
Professional aesthetic treatments
Regenerative skincare formulations
Sensitive skin rehabilitation products
Premium cosmetic preparations
FAQs About 3000 Da Hydrolyzed Sodium Hyaluronate
What specific advantages does 3000 Da molecular weight offer for skincare?
The 3000 Da molecular weight represents the optimal balance for skin penetration, allowing effective transit through the stratum corneum while maintaining significant water-binding capacity. This enables delivery of hydration to living epidermal layers where it can directly influence cellular moisture balance and barrier function.
How does enzymatic hydrolysis differ from other methods for producing low molecular weight HA?
Our proprietary enzymatic hydrolysis uses specific hyaluronidases that cleave HA chains at controlled positions, preserving the bioactive structure while achieving precise molecular weight reduction. This method avoids random degradation and maintains the natural glycosidic bonds essential for biological recognition and function.
What formulation considerations are unique to 3000 Da hydrolyzed sodium hyaluronate?
Due to its low molecular weight and high bioavailability, we recommend usage levels of 0.5%-2.0% in serums and 0.2%-1.0% in creams. It demonstrates enhanced stability in electrolyte-rich environments and shows superior compatibility with penetration enhancers and other bioactive compounds.
Can 3000 Da HA be combined with other molecular weights for synergistic effects?
Absolutely. Many advanced formulations combine our 3000 Da HA with medium (100,000-500,000 Da) and high (1,000,000+ Da) molecular weights to create a multi-depth hydration matrix that addresses moisture needs from the skin surface to the deeper epidermal layers.
What clinical evidence supports the efficacy of 3000 Da hydrolyzed sodium hyaluronate?
Independent studies demonstrate that 3000 Da HA achieves 3-5 times greater skin retention compared to standard HA, with significantly improved hydration parameters measured by corneometry and enhanced skin elasticity observed in viscoelasticity testing after 4 weeks of regular use.
Why Choose Runxin for Hydrolyzed Sodium Hyaluronate
28 Years of Hydrolysis Expertise: Specialized experience in controlled molecular weight reduction since 1998
Precision Manufacturing: Proprietary technology for consistent 3000 Da production
Comprehensive Quality Assurance: Full certification under cGMP, ISO9001, ISO22000, ISO13485, HACCP, HALAL, and FSSC22000
Advanced Analytical Capabilities: Sophisticated molecular weight verification methods
Technical Partnership: Expert guidance for formulation development and optimization
Partner with Hydrolysis Technology Innovators
Choose Runxin for your 3000 Da hydrolyzed sodium hyaluronate requirements and leverage our 28 years of specialized manufacturing expertise. Contact us today to request samples, analytical certificates, or discuss your specific application challenges. Experience the transformative potential of precisely engineered low molecular weight hyaluronic acid from an industry pioneer with nearly three decades of technological leadership.

Manufacturer Profile: Runxin – Precision Hydrolysis Specialists Since 1998
Runxin brings 28 years of focused expertise in advanced hyaluronic acid technologies, specializing in controlled molecular weight sodium hyaluronate production. Our sophisticated manufacturing facilities maintain comprehensive international certifications including cGMP, ISO9001, ISO22000, ISO13485, HACCP, HALAL, and FSSC22000, with specialized capabilities in enzymatic hydrolysis processes. Serving advanced skincare and pharmaceutical developers across 70+ countries, we combine proprietary hydrolysis technology with precision purification methods to deliver low molecular weight sodium hyaluronate with verified molecular characteristics and exceptional bioavailability.
Product Overview: 3000 Da Hydrolyzed Sodium Hyaluronate
Runxin's 3000 Da Hydrolyzed Sodium Hyaluronate represents a breakthrough in low molecular weight HA technology through controlled enzymatic hydrolysis. This precisely engineered material undergoes specialized processing to achieve a consistent molecular weight of 3000 Da (±500 Da), enabling superior skin penetration and cellular-level hydration. The proprietary hydrolysis process preserves the biological activity while significantly reducing molecular size, making it particularly effective for advanced skincare formulations targeting deep epidermal delivery and enhanced bioavailability.


Key Advantages
Precise Molecular Control: Consistent 3000 Da molecular weight through proprietary hydrolysis
Enhanced Skin Penetration: Optimal size for efficient transdermal delivery
Cellular-Level Hydration: Reaches deeper skin layers for fundamental moisturization
Preserved Bioactivity: Maintains HA's natural water-binding capacity
Formulation Versatility: Excellent compatibility with various delivery systems
Technical Specifications
Appearance: White to off-white fine powder
Molecular Weight: 3000 Da (±500 Da)
Purity: ≥98% (HPLC)
Loss on Drying: ≤6%
pH (1% solution): 5.8-6.8
Viscosity (1% solution): 20-80 mPa·s
Protein Content: ≤0.02%
Heavy Metals: ≤3 ppm
Microbiological Profile:
Total Plate Count: <50 CFU/g
Yeast & Mold: <10 CFU/g
E. coli: Absent in 10g
Salmonella: Absent in 25g
Solubility: ≥99.5% in water
Particle Size: 150-300 mesh
Certifications: cGMP, ISO9001, ISO22000, ISO13485, HACCP, HALAL, FSSC22000
Applications
Advanced anti-aging serums with deep penetration
Targeted dermal delivery systems
Professional aesthetic treatments
Regenerative skincare formulations
Sensitive skin rehabilitation products
Premium cosmetic preparations
FAQs About 3000 Da Hydrolyzed Sodium Hyaluronate
What specific advantages does 3000 Da molecular weight offer for skincare?
The 3000 Da molecular weight represents the optimal balance for skin penetration, allowing effective transit through the stratum corneum while maintaining significant water-binding capacity. This enables delivery of hydration to living epidermal layers where it can directly influence cellular moisture balance and barrier function.
How does enzymatic hydrolysis differ from other methods for producing low molecular weight HA?
Our proprietary enzymatic hydrolysis uses specific hyaluronidases that cleave HA chains at controlled positions, preserving the bioactive structure while achieving precise molecular weight reduction. This method avoids random degradation and maintains the natural glycosidic bonds essential for biological recognition and function.
What formulation considerations are unique to 3000 Da hydrolyzed sodium hyaluronate?
Due to its low molecular weight and high bioavailability, we recommend usage levels of 0.5%-2.0% in serums and 0.2%-1.0% in creams. It demonstrates enhanced stability in electrolyte-rich environments and shows superior compatibility with penetration enhancers and other bioactive compounds.
Can 3000 Da HA be combined with other molecular weights for synergistic effects?
Absolutely. Many advanced formulations combine our 3000 Da HA with medium (100,000-500,000 Da) and high (1,000,000+ Da) molecular weights to create a multi-depth hydration matrix that addresses moisture needs from the skin surface to the deeper epidermal layers.
What clinical evidence supports the efficacy of 3000 Da hydrolyzed sodium hyaluronate?
Independent studies demonstrate that 3000 Da HA achieves 3-5 times greater skin retention compared to standard HA, with significantly improved hydration parameters measured by corneometry and enhanced skin elasticity observed in viscoelasticity testing after 4 weeks of regular use.
Why Choose Runxin for Hydrolyzed Sodium Hyaluronate
28 Years of Hydrolysis Expertise: Specialized experience in controlled molecular weight reduction since 1998
Precision Manufacturing: Proprietary technology for consistent 3000 Da production
Comprehensive Quality Assurance: Full certification under cGMP, ISO9001, ISO22000, ISO13485, HACCP, HALAL, and FSSC22000
Advanced Analytical Capabilities: Sophisticated molecular weight verification methods
Technical Partnership: Expert guidance for formulation development and optimization
Partner with Hydrolysis Technology Innovators
Choose Runxin for your 3000 Da hydrolyzed sodium hyaluronate requirements and leverage our 28 years of specialized manufacturing expertise. Contact us today to request samples, analytical certificates, or discuss your specific application challenges. Experience the transformative potential of precisely engineered low molecular weight hyaluronic acid from an industry pioneer with nearly three decades of technological leadership.
