20kDa Sodium Hyaluronate
RUNXIN BIOTECH
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Product Description
Our 20,000 Da Sodium Hyaluronate is a low molecular weight hyaluronic acid sodium salt, meticulously produced through advanced fermentation and purification processes. This white to off-white powder is engineered for high-performance applications where excellent solubility, rapid hydration, and formulation compatibility are essential. Manufactured in an ISO & cGMP-certified facility, it guarantees consistent quality, high purity, and reliable batch-to-batch uniformity, making it a versatile raw material for various industries including cosmetics, nutraceuticals, and pharmaceuticals.
Key Advantages
- Controlled Molecular Weight: Precisely calibrated at 20,000 Da for targeted application performance.
- High Purity & Compliance: Produced under strict cGMP, ISO22000, FSSC22000, and HALAL certifications; free from impurities, additives, and animal-derived ingredients (option available).
- Superior Solubility: Dissolves quickly in water-based formulations, reducing processing time and improving production efficiency.
- Customizable Solutions: Available in standard and customized specifications including particle size and packaging.
Technical Specifications
- Appearance: White to off-white powder
- Molecular Weight: ~20,000 Da
- Purity (HPLC): ≥95%
- Loss on Drying: ≤10%
- pH (1% solution): 6.0 - 7.5
- Microbiological Limits: Total plate count <100 CFU/g, Yeast & mold <10 CFU/g
- Solubility: Easily soluble in water
- Certifications: ISO9001, cGMP, ISO22000, FSSC22000, HALAL
Typical Applications
- Cosmetic Serums & Creams: Used in moisturizing, anti-aging, and repairing skincare products for enhanced skin feel and performance.
- Functional Food & Beverages: Incorporated into health supplements and drinkables for their material characteristics.
- Pharmaceuticals: Suitable as an excipient or functional ingredient in certain drug delivery systems.
- Biomedical Research: Serves as a raw material in cell culture media and biochemical assays.
FAQ (Frequently Asked Questions)
1. Q: How is 20 KDa Sodium Hyaluronate categorized in terms of molecular size?
A: With a molecular weight of 20,000 Daltons, it is classified as a Very Low Molecular Weight (VLMW) or Oligo-Hyaluronate. This places it at the lowest end of the hyaluronate molecular weight spectrum.
2. Q: What is a key physical difference between 20 KDa and higher MW Sodium Hyaluronate in solution?
A: The key difference is viscosity. A solution of 20 KDa Sodium Hyaluronate will have very low viscosity, appearing almost watery even at concentrations where higher MW versions would form a thick gel. This impacts its handling and application in formulations.
3. Q: What is the typical production process for achieving a low MW like 20 KDa?
A: Producing 20 KDa typically requires an additional step called depolymerization after fermentation. This process involves carefully breaking down (hydrolyzing) larger, native hyaluronate chains into consistently smaller fragments using enzymatic or chemical methods to achieve the target low molecular weight.
4. Q: How does the function of 20 KDa Sodium Hyaluronate in a formula differ from a high MW version?
A: While high MW hyaluronate acts primarily as a surface film-former and viscosity enhancer, 20 KDa's primary function is often as a humectant and moisture regulator due to its high number of water-binding sites per unit of mass and its small molecular size.
5. Q: In what advanced applications is 20 KDa Sodium Hyaluronate being researched?
A: Beyond topical formulations, its low molecular weight makes it a subject of research in areas like nutraceuticals for oral supplementation, drug delivery systems where it can act as a carrier, and certain biomedical applications due to its potential biological signaling properties.
Why Choose Runxin Bio?
- Over 28 Years of Expertise: Since 1998, we have specialized in the research, production, and application of sodium hyaluronate and chondroitin sulfate, serving 3000+ global enterprises.
- Internationally Recognized Quality System: We hold multiple certifications including cGMP, ISO13485, FSSC22000, HALAL, NSF,and FDA registration, ensuring product safety, traceability, and compliance for global markets.
- Reliable Supply Chain and Customization Capability: We support both standard and tailor-made orders with stable production capacity, strict QC protocols, and responsive customer service, making us a trusted long-term partner for brands and manufacturers worldwide.
Ready to Partner with a Trusted Supplier?
Contact us today to request samples, technical documents, or discuss your specific requirements. Let’s collaborate to innovate and grow together.
Product Description
Our 20,000 Da Sodium Hyaluronate is a low molecular weight hyaluronic acid sodium salt, meticulously produced through advanced fermentation and purification processes. This white to off-white powder is engineered for high-performance applications where excellent solubility, rapid hydration, and formulation compatibility are essential. Manufactured in an ISO & cGMP-certified facility, it guarantees consistent quality, high purity, and reliable batch-to-batch uniformity, making it a versatile raw material for various industries including cosmetics, nutraceuticals, and pharmaceuticals.
Key Advantages
- Controlled Molecular Weight: Precisely calibrated at 20,000 Da for targeted application performance.
- High Purity & Compliance: Produced under strict cGMP, ISO22000, FSSC22000, and HALAL certifications; free from impurities, additives, and animal-derived ingredients (option available).
- Superior Solubility: Dissolves quickly in water-based formulations, reducing processing time and improving production efficiency.
- Customizable Solutions: Available in standard and customized specifications including particle size and packaging.
Technical Specifications
- Appearance: White to off-white powder
- Molecular Weight: ~20,000 Da
- Purity (HPLC): ≥95%
- Loss on Drying: ≤10%
- pH (1% solution): 6.0 - 7.5
- Microbiological Limits: Total plate count <100 CFU/g, Yeast & mold <10 CFU/g
- Solubility: Easily soluble in water
- Certifications: ISO9001, cGMP, ISO22000, FSSC22000, HALAL
Typical Applications
- Cosmetic Serums & Creams: Used in moisturizing, anti-aging, and repairing skincare products for enhanced skin feel and performance.
- Functional Food & Beverages: Incorporated into health supplements and drinkables for their material characteristics.
- Pharmaceuticals: Suitable as an excipient or functional ingredient in certain drug delivery systems.
- Biomedical Research: Serves as a raw material in cell culture media and biochemical assays.
FAQ (Frequently Asked Questions)
1. Q: How is 20 KDa Sodium Hyaluronate categorized in terms of molecular size?
A: With a molecular weight of 20,000 Daltons, it is classified as a Very Low Molecular Weight (VLMW) or Oligo-Hyaluronate. This places it at the lowest end of the hyaluronate molecular weight spectrum.
2. Q: What is a key physical difference between 20 KDa and higher MW Sodium Hyaluronate in solution?
A: The key difference is viscosity. A solution of 20 KDa Sodium Hyaluronate will have very low viscosity, appearing almost watery even at concentrations where higher MW versions would form a thick gel. This impacts its handling and application in formulations.
3. Q: What is the typical production process for achieving a low MW like 20 KDa?
A: Producing 20 KDa typically requires an additional step called depolymerization after fermentation. This process involves carefully breaking down (hydrolyzing) larger, native hyaluronate chains into consistently smaller fragments using enzymatic or chemical methods to achieve the target low molecular weight.
4. Q: How does the function of 20 KDa Sodium Hyaluronate in a formula differ from a high MW version?
A: While high MW hyaluronate acts primarily as a surface film-former and viscosity enhancer, 20 KDa's primary function is often as a humectant and moisture regulator due to its high number of water-binding sites per unit of mass and its small molecular size.
5. Q: In what advanced applications is 20 KDa Sodium Hyaluronate being researched?
A: Beyond topical formulations, its low molecular weight makes it a subject of research in areas like nutraceuticals for oral supplementation, drug delivery systems where it can act as a carrier, and certain biomedical applications due to its potential biological signaling properties.
Why Choose Runxin Bio?
- Over 28 Years of Expertise: Since 1998, we have specialized in the research, production, and application of sodium hyaluronate and chondroitin sulfate, serving 3000+ global enterprises.
- Internationally Recognized Quality System: We hold multiple certifications including cGMP, ISO13485, FSSC22000, HALAL, NSF,and FDA registration, ensuring product safety, traceability, and compliance for global markets.
- Reliable Supply Chain and Customization Capability: We support both standard and tailor-made orders with stable production capacity, strict QC protocols, and responsive customer service, making us a trusted long-term partner for brands and manufacturers worldwide.
Ready to Partner with a Trusted Supplier?
Contact us today to request samples, technical documents, or discuss your specific requirements. Let’s collaborate to innovate and grow together.
