200 kDa Hydrolyzed Sodium Hyaluronate | Runxin Bio-Fermentation Technology

Manufacturer Profile: Runxin – Precision Hydrolysis Specialists Since 1998
Runxin brings 28 years of manufacturing excellence in bio-fermented sodium hyaluronate, with specialized expertise in controlled molecular weight hydrolysis. Our advanced fermentation and hydrolysis facilities maintain comprehensive international certifications including cGMP, ISO9001, ISO22000, ISO13485, HACCP, HALAL, and FSSC22000, with particular focus on precision molecular weight control. Serving premium cosmetic, pharmaceutical, and nutraceutical companies across 70+ countries, we combine proprietary bio-fermentation with enzymatic hydrolysis technologies to deliver 200 kDa sodium hyaluronate with verified molecular characteristics and optimized biological activity.

Product Overview: 200 kDa Hydrolyzed Sodium Hyaluronate
Runxin's 200 kDa Hydrolyzed Sodium Hyaluronate represents an optimally balanced molecular weight achieved through controlled enzymatic hydrolysis of bio-fermented HA. This precisely engineered product undergoes specialized processing to maintain consistent 200 kDa molecular weight (±15 kDa), creating an ideal balance between skin penetration and moisture retention capabilities. The controlled hydrolysis process preserves the bioactive structure while achieving the target molecular size, making it particularly effective for formulations requiring both effective epidermal delivery and sustained hydration.

Key Advantages

• Precision Molecular Weight: Consistent 200 kDa through controlled enzymatic hydrolysis

• Balanced Performance: Optimal equilibrium between penetration and moisturization

• Enhanced Bioavailability: Improved skin absorption while maintaining functional integrity

• Process Control: Proprietary hydrolysis ensures reproducible molecular characteristics

• Multi-Layer Efficacy: Effective in both stratum corneum and viable epidermis

Technical Specifications

• Appearance: White to off-white free-flowing powder

• Molecular Weight: 200 kDa (±15 kDa)

• Purity: ≥96% (HPLC)

• Loss on Drying: ≤8%

• pH (1% solution): 6.0-7.0

• Viscosity (1% solution): 300-600 mPa·s

• Protein Content: ≤0.05%

• Heavy Metals: ≤5 ppm

• Microbiological Profile:

• Total Plate Count: <100 CFU/g

• Yeast & Mold: <10 CFU/g

• E. coli: Absent in 10g

• Salmonella: Absent in 25g

• Solubility: ≥98% in water

• Particle Size: 100-180 mesh

• Certifications: cGMP, ISO9001, ISO22000, ISO13485, HACCP, HALAL, FSSC22000

Applications

• Advanced skincare serums with balanced penetration

• Anti-aging formulations requiring multi-layer hydration

• Professional aesthetic products

• Sensitive skin treatments

• Nutraceutical formulations

• Premium cosmetic preparations

FAQs About 200 kDa Hydrolyzed Sodium Hyaluronate

1. What specific benefits does 200 kDa molecular weight provide in skincare?
   The 200 kDa molecular weight represents the optimal threshold for balanced performance, enabling effective penetration into the upper epidermal layers while maintaining significant water-binding capacity and film-forming properties. This dual functionality provides immediate surface hydration while delivering moisture to deeper skin levels.

2. How does enzymatic hydrolysis ensure precise 200 kDa molecular weight control?
   Our proprietary enzymatic methodology utilizes specific hyaluronidases that cleave HA chains at controlled positions, enabling accurate molecular weight targeting. Advanced process monitoring and real-time viscosity measurements ensure consistent 200 kDa output with minimal molecular weight distribution.

3. What formulation advantages does 200 kDa HA offer compared to other molecular weights?
   This specific molecular weight demonstrates ideal viscosity characteristics for easy formulation, excellent stability in various systems, and balanced performance that eliminates the need for blending multiple molecular weights. It provides both immediate and sustained hydration without compromising sensory properties.

4. Can 200 kDa sodium hyaluronate be used in combination with other active ingredients?
   Absolutely. Its balanced molecular characteristics make it an excellent carrier for other active ingredients, enhancing their distribution and bioavailability in the skin. It shows particular synergy with peptides, vitamins, and plant extracts.

5. What analytical methods verify the consistent 200 kDa molecular weight?
   We employ multiple analytical techniques including SEC-MALS (Size Exclusion Chromatography with Multi-Angle Light Scattering), intrinsic viscosity measurements, and GPC analysis to ensure each batch maintains the specified 200 kDa target with narrow molecular weight distribution.

Why Choose Runxin for 200 kDa Hydrolyzed Sodium Hyaluronate

• 28 Years of Hydrolysis Expertise: Specialized experience in controlled molecular weight production since 1998

• Proprietary Enzymatic Technology: Precision hydrolysis for accurate molecular weight control

• Bio-Fermentation Derived: Pure, animal-free starting material

• Comprehensive Quality Assurance: Full certification under cGMP, ISO9001, ISO22000, ISO13485, HACCP, HALAL, and FSSC22000

• Global Technical Support: Formulation guidance and application development assistance

Partner with Molecular Weight Precision Specialists
Choose Runxin for your 200 kDa hydrolyzed sodium hyaluronate requirements and leverage our 28 years of specialized manufacturing expertise. Contact us today to request samples, analytical documentation, or discuss your specific application needs. Experience the advantages of precisely engineered molecular weight hyaluronic acid from an industry leader with nearly three decades of technological innovation and quality excellence.