4D Sodium Hyaluronate Solution | Runxin 28 Years Source Factory

Manufacturer Profile: Runxin – Multi-Dimensional HA Innovators Since 1998
Runxin brings 28 years of manufacturing excellence in advanced sodium hyaluronate solutions, with pioneering expertise in multi-molecular weight technology. Our state-of-the-art production facilities maintain comprehensive international certifications including cGMP, ISO9001, ISO22000, ISO13485, HACCP, HALAL, and FSSC22000, with specialized capabilities in precision molecular weight engineering. Serving leading cosmetic, pharmaceutical, and aesthetic brands across 70+ countries, we combine proprietary fractionation technology with advanced solution stabilization methods to deliver 4D hyaluronic acid solutions that redefine hydration performance.

Product Overview: 4D Sodium Hyaluronate Solution
Runxin's 4D Sodium Hyaluronate Solution represents a breakthrough in multi-depth hydration technology, integrating four precisely calibrated molecular weights (10 kDa, 50 kDa, 200 kDa, and 1,000 kDa) in a stabilized aqueous solution. This advanced formulation undergoes proprietary stabilization processing to ensure compatibility and synergistic performance across all molecular fractions. The ready-to-use solution format provides immediate formulation convenience while guaranteeing the optimal ratio of molecular weights for comprehensive skin hydration from surface to deep epidermal layers.

Key Advantages

• Quad-Molecular Action: Four precisely balanced molecular weights target different skin depths

• Ready-to-Use Solution: Pre-dissolved format ensures easy formulation and batch consistency

• Synergistic Hydration: Multi-depth moisturization from stratum corneum to basal layer

• Enhanced Stability: Proprietary stabilization technology extends shelf life and performance

• Time-Saving Production: Eliminates dissolution steps and ensures uniform distribution

Technical Specifications

• Appearance: Clear, colorless to slightly opalescent solution

• Solid Content: 1.5% ± 0.2%

• Molecular Weight Distribution:

• 10 kDa (25%) - Deep epidermal penetration

• 50 kDa (25%) - Intercellular hydration

• 200 kDa (25%) - Surface-to-mid layer delivery

• 1,000 kDa (25%) - Surface film formation

• pH: 5.8-6.8

• Viscosity: 800-1,500 mPa·s (25°C)

• Preservative System: Phenoxyethanol & Ethylhexylglycerin (or preservative-free options)

• Heavy Metals: ≤2 ppm

• Microbiological Profile:

• Total Plate Count: <50 CFU/mL

• Yeast & Mold: <10 CFU/mL

• E. coli: Absent in 10mL

• Storage Conditions: 2-25°C, protect from freezing

• Shelf Life: 24 months in original packaging

• Certifications: cGMP, ISO9001, ISO22000, ISO13485, HACCP, HALAL, FSSC22000

Applications

• Advanced multi-depth hydrating serums

• Professional aesthetic treatments

• Anti-aging and rejuvenating formulations

• Medical skincare and post-procedure care

• Sensitive skin hydration products

• Premium cosmetic preparations

FAQs About 4D Sodium Hyaluronate Solution

1. What distinguishes 4D hyaluronic acid from traditional single-molecular weight HA?
   4D technology integrates four molecular weights that work synergistically to hydrate different skin layers simultaneously. The 10 kDa fraction penetrates deeply for cellular-level hydration, 50 kDa targets intercellular spaces, 200 kDa works in mid-layers, and 1,000 kDa forms a protective surface film, creating comprehensive moisture coverage unmatched by single-weight formulations.

2. How does the solution format benefit cosmetic formulation processes?
   The pre-dissolved solution eliminates time-consuming hydration steps, ensures perfect molecular weight distribution in every batch, reduces manufacturing variations, and guarantees consistent performance. This ready-to-use format also minimizes dust exposure and improves production efficiency while maintaining exact molecular weight ratios.

3. Can the molecular weight ratios in the 4D solution be customized?
   Yes, with our 28 years of fractionation expertise, we offer customized molecular weight combinations and ratio adjustments to meet specific formulation requirements. Common variations include adjusting the balance between penetrating and film-forming fractions for different product types and target consumer needs.

4. What stability testing supports the 24-month shelf life claim?
   Our comprehensive stability program includes real-time and accelerated testing under ICH guidelines, demonstrating consistent molecular weight integrity, viscosity stability, and microbiological safety over 24 months. Each batch undergoes rigorous challenge testing to validate preservation efficacy.

5. How does your quality system ensure consistent performance across production batches?
   Our integrated quality management, certified under cGMP, ISO9001, ISO22000, ISO13485, HACCP, HALAL, and FSSC22000, includes in-process controls for each molecular weight fraction, final blend verification, and performance testing to ensure every batch delivers identical hydration performance and molecular characteristics.

Why Choose Runxin for 4D Sodium Hyaluronate Solution

• 28 Years of Molecular Engineering: Expertise in precise molecular weight control since 1998

• Proprietary Fractionation Technology: Advanced separation and stabilization methods

• Ready-to-Use Convenience: Pre-optimized solution saves formulation time and cost

• Comprehensive Quality Assurance: Full certification under cGMP, ISO9001, ISO22000, ISO13485, HACCP, HALAL, and FSSC22000

• Technical Partnership: Expert guidance on implementation and formulation optimization

Partner with Multi-Dimensional HA Pioneers
Choose Runxin for your 4D sodium hyaluronate solution requirements and leverage our 28 years of source factory expertise. Contact us today to request samples, stability data, or discuss your specific formulation challenges. Experience the future of multi-depth hydration technology from an industry innovator committed to quality, performance, and customer success.