Acetylated Sodium Hyaluronate-Runxin Verified Purity Global Supply

Manufacturer Profile: Runxin – Molecular Innovation Leaders Since 1998
Runxin brings 28 years of specialized expertise in advanced hyaluronic acid modification technologies, with pioneering capabilities in acetylated sodium hyaluronate production. Our cutting-edge modification facilities maintain comprehensive international certifications including cGMP, ISO9001, ISO22000, ISO13485, HACCP, HALAL, and FSSC22000, with dedicated focus on molecular structure engineering. Serving innovative cosmetic, pharmaceutical, and dermal delivery brands across 70+ countries, we combine proprietary acetylation technology with precision quality control to deliver acetylated sodium hyaluronate with enhanced functionality and superior performance characteristics.

Product Overview: Acetylated Sodium Hyaluronate
Runxin's Acetylated Sodium Hyaluronate represents a breakthrough in HA modification through controlled introduction of acetyl groups to the hyaluronic acid molecule. This advanced modification significantly enhances lipid solubility and skin affinity while maintaining the inherent water-binding capacity of native HA. With acetylation degrees ranging from 80-95% and molecular weights from 50,000 to 1,500,000 Da, our product delivers unprecedented penetration capabilities and prolonged skin residence time, making it ideal for advanced skincare formulations requiring enhanced bioavailability and long-lasting effects.

Key Advantages

• Enhanced Skin Affinity: Acetyl groups dramatically improve compatibility with skin lipids

• Superior Penetration: Balanced lipophilic-hydrophilic properties enable efficient stratum corneum transit

• Prolonged Efficacy: Modified structure resists enzymatic degradation for sustained activity

• Multi-Phase Compatibility: Effective in both oil and water-based formulations

• Synergistic Performance: Enhances delivery and efficacy of co-formulated active ingredients

Technical Specifications

• Appearance: White to off-white fluffy powder

• Acetylation Degree: 80-95%

• Molecular Weight: 50,000-1,500,000 Da (customizable)

• Purity: ≥92% (HPLC)

• Loss on Drying: ≤7%

• pH (1% solution): 5.5-6.5

• Viscosity (1% solution): 100-2,000 mPa·s (depending on molecular weight)

• Protein Content: ≤0.03%

• Heavy Metals: ≤3 ppm

• Microbiological Profile:

• Total Plate Count: <100 CFU/g

• Yeast & Mold: <10 CFU/g

• E. coli: Absent in 10g

• Salmonella: Absent in 25g

• Solubility: Dispersible in both aqueous and oil phases

• Certifications: cGMP, ISO9001, ISO22000, ISO13485, HACCP, HALAL, FSSC22000

Applications

• Advanced anti-aging serums with enhanced penetration

• Lipid-based skincare formulations

• Targeted dermal delivery systems

• Professional aesthetic treatments

• Long-lasting moisturizing products

• Premium cosmetic preparations

FAQs About Acetylated Sodium Hyaluronate

1. What specific benefits does acetylation provide compared to standard hyaluronic acid?
   Acetylation transforms hyaluronic acid into an amphiphilic molecule that bridges water and lipid compatibility. This modification significantly enhances skin adhesion, improves penetration through the stratum corneum, increases resistance to hyaluronidase degradation, and extends skin residence time by 3-5 times compared to conventional HA.

2. How does your acetylation technology ensure consistent modification quality?
   Our proprietary acetylation process utilizes controlled reaction conditions with real-time monitoring of modification parameters. Advanced NMR and FTIR analysis verifies acetylation degree and position, ensuring consistent molecular structure and performance across all production batches while maintaining cGMP, ISO9001, ISO22000, ISO13485, HACCP, HALAL, and FSSC22000 compliance.

3. Can acetylated sodium hyaluronate be used in oil-based formulations?
   Absolutely. The introduction of acetyl groups creates unique amphiphilic properties that enable effective performance in anhydrous systems, oil phases, and traditional emulsions. This versatility makes it particularly valuable for innovative formulations that challenge conventional HA limitations.

4. What is the recommended usage percentage for optimal results?
   Recommended usage ranges from 0.1-2.0% depending on formulation type and desired effects. For serums: 0.5-2.0%, creams: 0.2-1.0%, lotions: 0.1-0.5%. The lower molecular weight versions typically require lower percentages due to enhanced penetration efficiency.

5. What clinical evidence supports the efficacy of acetylated sodium hyaluronate?
   Independent clinical studies demonstrate that acetylated HA provides significantly improved skin hydration (up to 45% better than conventional HA), enhanced elasticity, reduced transepidermal water loss, and visible wrinkle reduction with effects lasting up to 8 hours longer than standard hyaluronic acid.

Why Choose Runxin for Acetylated Sodium Hyaluronate

• 28 Years of Modification Expertise: Pioneering experience in HA molecular engineering since 1998

• Proprietary Acetylation Technology: Precision control of modification degree and position

• Comprehensive Quality Systems: Full certification under cGMP, ISO9001, ISO22000, ISO13485, HACCP, HALAL, and FSSC22000

• Customization Capabilities: Tailored acetylation degrees and molecular weights

• Technical Leadership: Expert guidance on formulation and application development

Partner with Molecular Modification Pioneers
Choose Runxin for your acetylated sodium hyaluronate requirements and leverage our 28 years of advanced modification expertise. Contact us today to request samples, technical documentation, or discuss your specific application challenges. Experience the transformative potential of acetylated hyaluronic acid technology from an industry leader committed to innovation, quality, and customer success.