2ml FOMEIZOR Non Cross-linked Hyaluronic Acid Injection for Horse Racing

What Is Non-Cross-linked Hyaluronic Acid Injection?

Non-Cross-linked Hyaluronic Acid Injection is a medical-grade, viscoelastic gel derived from bacterial fermentation—free of animal origin. Unlike cross-linked HA formulations used in dermal fillers, this product maintains its natural linear molecular structure, delivering superior biocompatibility and immediate lubricating effects.

As the primary component of synovial fluid in joints, hyaluronic acid acts as a biological lubricant and shock absorber. Non-cross-linked HA closely mimics the body's own physiological fluids, making it ideal for applications requiring rapid integration and natural performance.

Key characteristics:

· Linear molecular structure without chemical cross-linking agents

· High biocompatibility and low immunogenic potential

· Rapid integration with body's natural tissues

· Excellent lubricating and cushioning properties

· Non-animal origin via Streptococcus bacterial fermentation

FOMEIZOR Brand Advantage:
FOMEIZOR, our flagship brand under Shandong Runxin Biotechnology, represents 28 years of dedicated research and manufacturing excellence in sodium hyaluronate products. Every batch undergoes rigorous quality control to ensure consistent purity, viscosity, and safety standards.

Non-Cross-linked HA Injection Specifications

FOMEIZOR Non-Cross-linked Hyaluronic Acid Injection is available in multiple specifications to meet diverse clinical requirements:

Technical Parameters:

· Molecular Weight: 600,000 – 1,500,000 Daltons (optimized for viscoelasticity)

· pH Range: 6.8 – 7.4 (physiological balance)

· Osmolarity: 280 – 320 mOsm/kg

· Endotoxin Level: < 0.5 EU/mL (ultra-pure standard)

· Sterility: Sterile, non-pyrogenic formulation

· Shelf Life: 24-36 months (sealed packaging, 2-30°C storage)

Packaging Options:

· Pre-filled syringes for immediate clinical use

· Vials for multi-dose preparation

· Custom private label packaging available for bulk orders

Applications: Where Non-Cross-linked HA Injection Works

FOMEIZOR Non-Cross-linked Hyaluronic Acid Injection serves four primary medical application areas:

1. Orthopedic Joint Lubrication

Intra-articular injection for viscosupplementation in osteoarthritis management:

Clinical Indications:

· Knee osteoarthritis (mild to moderate)

· Hip joint degeneration

· Shoulder adhesive capsulitis

· Ankle and wrist joint wear

Treatment Protocol:

· Standard course: 3-5 weekly injections (2-3 mL per joint)

· Single high-dose protocol: 3 mL one-time administration

· Effect duration: 3-6 months depending on severity

Mechanism:
Non-cross-linked HA restores synovial fluid viscosity, reduces friction between articular cartilage surfaces, and provides cushioning against mechanical stress. Clinical studies demonstrate pain reduction of 28-54% and improved joint function lasting up to six months post-treatment.

2. Ophthalmic Surgery

Viscoelastic protection during surgical procedures:

Surgical Applications:

· Cataract extraction and IOL implantation

· Corneal transplant surgery

· Glaucoma filtration procedures

· Retinal attachment surgery

· Anterior segment reconstruction

Benefits:
The gel maintains intraoperative space, protects corneal endothelium from mechanical trauma, and facilitates tissue manipulation. Its high molecular weight provides optimal cohesion and space-maintaining properties while remaining easily removable post-procedure.

3. Veterinary Medicine

Safe and effective for companion animals:

Animal Applications:

· Canine and feline osteoarthritis

· Equine joint therapy

· Post-surgical joint lubrication

· Anti-inflammatory support for degenerative joint disease

Non-cross-linked HA offers excellent safety profiles in veterinary applications, with minimal adverse reactions reported across multiple species.

4. Anti-Adhesion Barrier

Post-surgical tissue protection:

Surgical Settings:

· Abdominal surgery

· Pelvic surgery

· Tendon and ligament repair

· Spinal procedures

The gel forms a temporary barrier between tissue planes, preventing abnormal fibrous adhesion formation while maintaining tissue hydration and promoting natural healing.

Why Choose Non-Cross-linked Over Cross-linked HA?

Understanding the differences helps healthcare professionals select the optimal product:

When Non-Cross-linked HA is Preferred:

· Joint viscosupplementation requiring biological fluid matching

· Ophthalmic surgery demanding clear visibility and easy removal

· Applications requiring rapid absorption and integration

· Patients with sensitivity concerns or history of adverse reactions

· Veterinary use requiring broad species compatibility

Certifications and Quality Assurance

Shandong Runxin Biotechnology maintains the highest international quality standards:

Manufacturing Certifications:

· ISO 13485:2016 – Medical Device Quality Management

· cGMP Compliance – Pharmaceutical-grade production standards

· CE Marking – European market authorization

· DMF – Active pharmaceutical ingredient documentation

Product Certifications:

· COSMOS – Natural and organic cosmetic standards

· HALAL – Islamic certification for Muslim markets

· SGS Verification – Third-party quality testing

Quality Control Measures:

· 100% batch inspection protocol

· Advanced GPC analysis for molecular weight verification

· Endotoxin and sterility testing per lot

· Complete traceability from raw materials to finished product

Our manufacturing facility spans 30,000+ square meters with 2,000+ square meters of Class 7 cleanrooms, producing 100,000+ units daily with consistent quality across all batches.

Frequently Asked Questions

Q: What is the difference between cross-linked and non-cross-linked hyaluronic acid?
A: Non-cross-linked HA maintains its natural linear structure without chemical cross-linking agents, providing superior biocompatibility and rapid integration. Cross-linked HA uses chemical bonds (typically BDDE) to create a 3D network, offering longer duration but higher viscosity. For medical applications requiring biological fluid matching, non-cross-linked is preferred.

Q: What specifications are available?
A: We offer 2 mL and 3 mL pre-filled syringes with concentrations ranging from 10-20 mg/mL. Custom specifications and bulk packaging are available for large orders.

Q: What is the minimum order quantity (MOQ)?
A: Standard MOQ varies by specification. Contact our team for specific requirements. We accommodate both small sample orders and large-scale commercial production.

Q: Do you provide OEM/ODM services?
A: Yes. We offer comprehensive OEM services including custom formulations, private label packaging, and brand development support. Our 26 years of experience ensures reliable partner integration.

Q: What certifications does your product hold?
A: FOMEIZOR Non-Cross-linked Hyaluronic Acid Injection carries CE, ISO 13485, HALAL, COSMOS, and DMF certifications, enabling market access across Europe, North America, Asia, and Middle East regions.

Q: What is the shelf life and storage requirement?
A: Product maintains stability for 24-36 months when stored sealed at 2-30°C. Do not freeze. Protect from direct sunlight.

Q: Is the product suitable for veterinary use?
A: Yes. Non-cross-linked HA demonstrates excellent safety profiles across multiple animal species, including canines, felines, and equines. Consult species-specific protocols for dosing.

Q: How quickly can orders be fulfilled?
A: Standard lead time is 2-4 weeks for standard specifications. Large-volume orders and custom packaging require 4-8 weeks. Express shipping available via DHL, FedEx, or EMS.

Partner With FOMEIZOR for Your HA Supply Chain

Whether you are a distributor establishing your product portfolio, a medical institution seeking reliable supply, or a brand builder developing custom solutions, FOMEIZOR delivers consistent quality and dependable partnership.

Our Commitment:

· End-to-end quality control from raw materials to finished product

· Flexible MOQ accommodating both market testing and large-scale production

· Complete technical documentation and regulatory support

· Responsive customer service with dedicated account management

· Competitive pricing backed by 28 years of manufacturing expertise

Contact Us Today:

Request a sample for evaluation or discuss your specific requirements with our technical team. We provide detailed product specifications, pricing, and shipping information tailored to your needs.

Shandong Runxin Biotechnology Co., Ltd. – 28 years dedicated to advancing hyaluronic acid applications for global healthcare. Quality products. Trusted partnership. Innovation driven.